Ghaneei M, Movahhedi M, Mirzadeh M, Adibi P. Probability for Differentiation of Blood Indices for Determination of
Iron Deficiency in Mihor Thalassemia Based on Red Cell
. JGUMS 1997; 6 (22) :1-6
URL:
http://journal.gums.ac.ir/article-1-1909-en.html
Abstract: (4349 Views)
ABSTRACT:
Minor beta-thalssemia is one of the frequent causes of microcytic anemia .To screen a large population for thalassemia traits, simple diagnostic tests are needed by which iron deficiency can be differentiated from the traits.
In a descriptive study data of complete blood count of 15000 men and 15000 women was measured by H*1 cell counter and evaluated; And several indices and formulae were checked to find out whether they are good discriminators or not. We found out that in a man with MCV<80 FL,RBC>7×106/mm3 and Hb<18 g/dl the probability of thalassemia traits is 90% with the same MCV in womman and a 106/mm3 RBC>6.5) 0.01 formula canxand Hb<16, the probability will be the same. Using (MCV)2 with ×MCH×help to screen the trait sensitivity of 100% in women, which was equal to value of MCV/RBC in men.
conclusion :The two above mentioned formula can be used as the first step of screening of minor beta thalassemia
Review Paper:
Research |
Subject:
Special Received: 2019/03/12 | Accepted: 2019/03/12 | Published: 2019/03/12