Volume 1, Issue 1 And 2 (4-1992)                   JGUMS 1992, 1(1 And 2): 11-18 | Back to browse issues page

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بیماری شیهان گزارش هفده مورد از رشت. JGUMS 1992; 1 (1 and 2) :11-18
URL: http://journal.gums.ac.ir/article-1-2022-en.html
Abstract:   (1657 Views)
SUMMARY
During eight years, 1359-1366, seventeen cases with Sheehan's disease was seen. The age of the patients at the time of postpartum hemorrhagic shock was 30±7( mean± 1 SD ) years and at admission was 41 ± 10 ( mean ± 1 SD) years . weakness , palor, and Amenorrhe a was the three most common presenting complaints . Nine patients was referred with the diagnosis of Sheehan's disease (4 cases), hypothyroidism ( 3 cases ), hypoglycemia ( 1 cases), and coma ( 1 cases ).
Clinially all of the patients had almost all the symptoms and signs of panhypopituitarism. Serum T4 was 2 ± 1.3 ( mean - 1 SD , normal range 4 - 12) mcg/dl , Serum TSH was 2 ±1.7 (mean ± 1 SD , normal range up to 5)/µ/ml, plasma cortisol was 3.5 ± 2.7 , normal range 4 - 24 ) mcg/dl.
After two weeks treatment with about 30 mg prednesolone per day treatment with levothyraxine was begun ; first with 25to 50 mcg daily , The 25 mcg increment perday every 4 to 6 weeks , till The replacement dose of about 1.8 mcg/kg/dug was achieved . Mean while the dose of prednesolone was tapered down to 5 to 7.5 mg a day. For replacement of estrogen and inducing menstural cycles, combiened estrogen and progestogen therapy can be instituted.
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Review Paper: Research | Subject: Special
Received: 2019/04/9 | Accepted: 2019/04/9 | Published: 2019/04/9

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