Volume 16, Issue 61 (4-2007)                   JGUMS 2007, 16(61): 90-95 | Back to browse issues page

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Khalili D, Boloki moghadam K, Fahim far N, Gharavi M. Survey of the Growth Disorder in Thalassemia Major Patients in Rasht-Iran. JGUMS 2007; 16 (61) :90-95
URL: http://journal.gums.ac.ir/article-1-403-en.html
Abstract:   (5975 Views)
Abstract Introduction: Growth disorder is a complex and multi-factorial problem which needs a precise assessment. In Thalassemia major there is much more growth disorder due to chronic anemia, Iron overload, endocrine dysfunctions and etc which can be prevented by accurate and regular treatment. Objective: In this study we wanted to evaluate height and weight disorders in order to guess clinical feature and condition of treatment in Thalassemia major patients. Materials and Methods: we measured height and weight of thalassemia major patients (height and weight < 5% were considered as a disorder) and some factors such as age, the age of first treatment, the number of visits (for transfusion therapy) and the number of transfused blood units in per year by interview, examination and survey of their files. Results: Among 392 patients, 42.3% of them had height under 5% and 37% had weight under 5%. Totally, 190 patients (48.5%) had growth disorder (height, weight or both). Sex had no significant relation with growth disorder. Most of disorders occurred in second decade of life. According to the logistic regression analysis, age, the age of first treatment had positive relations and the number of visits in per year had a negative relation with growth disorder. Conclusion: Comparing these results with developed countries showed that we are in a backward state and our patients need more precise treatment.
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Review Paper: Research | Subject: Special
Received: 2014/01/1 | Accepted: 2014/01/1 | Published: 2014/01/1

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