Volume 19, Issue 75 (10-2010)                   jour guilan uni med sci 2010, 19(75): 86-93 | Back to browse issues page

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Survey of Polyethylene Glycol Effects on Serum Electrolytes . jour guilan uni med sci. 2010; 19 (75) :86-93
URL: http://journal.gums.ac.ir/article-1-191-en.html
Abstract:   (5446 Views)
Abstract Introduction: Colonoscopy and bowel preparation caused a number of serum electrolytes changes that may be dangerous in heart and kidney diseases and elderly patients. Objective: To determine the effect of serum electrolytes in patients who underwent colonoscopy and bowel preparation with PEG (Polyethylene Glycol) in Tehran Imam Khomeini hospital in 2008. Materials and Methods: Fifty nine patients who had been selected for elective colonoscopy after the detection of exclusion criteria were assessed prospectively. Serum level of sodium and potassium were analysed before bowel preparation with PEG (To), before colonoscopy (T1) and immediately after it (T2). Serum calcium and phosphorus levels were measured just before and after PEG. Results: Four patients (6.8%) did not follow the research protocol and were excluded. Four patients (6.8%) developed hyponatremia in T1 that continued in T2. There were no significant differences in prevalence of Hyponatremia and means of sodium serum levels in To, T1 and T2. Although there was a significant trend to decreased means of potassium levels of T2 versus T1 (P<0.01), but the maximum prevalence of Hypakalemia was in T1 (10.9%) with only 3.8% new Hypokaliemia in T2 and there was no significant difference. The prevalence of Hypocalcemia after PEG was 24% but there was no significant decrease. 36% of patients developed Hypophosphatemia after PEG preparation with a significant decrease in mean of serum Phosphorus level (P<0.05). There was no significant relationship between electrolytes changes with age and sex. Conclusion: The serum electrolyte changes showed that preparation with PEG is a risk factor for development of Hypophosphatemia Colonoscopy and preparation with PEG may cause a significant decrease in potassium serum level
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Type of Study: Research | Subject: Special
Received: 2013/11/16 | Accepted: 2013/11/16 | Published: 2013/11/16

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