Volume 17, Issue 68 (1-2009)                   JGUMS 2009, 17(68): 14-21 | Back to browse issues page

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1- Guilan University of Medical Sciences , m_jafroodi@yahoo.com
2- Guilan University of Medical Sciences
Abstract:   (7244 Views)
Abstract Introduction: Although cancers occur rarely in children, they considered as the second cause of death in children under 14 years old. Cancers in children differ markedly from those in adults according their nature, distribution, and prognosis. Acute Lymphoblastic leukemia and lymphoma account about 40%, central nervous system tumors consist of 30% and embryonal malignancies and sarcoma account for about another 10% of all pediatric cancers. Objective: Epidemiologic evaluation of pediatric causes of cancer who referred to 17 Sharivar hospital in Rasht during 2001-2007. Materials and Methods: This descriptive cross- sectional study was carried out in 17 Sharivar hospital in Rasht from 2001-2007 .All cases of pediatric cancers were included in this study. All information about the age, sex, type of cancers and residence of patients were collected from their medical records 152 forms were completed and the data were analyzed by SPSS. Results: Among 152 patients with different types of malignancy there were 89 male (58.6%) and 63 female (41.4%). Ratio of male to female was 1.36 in acute lymphoblastic leukemia, 0.71 in AML, 4 in non-hokin ulmphoma (NHL) , 0.33 in sarcoma. 1.6 in Wilms Tumor, 2 in Hodgkin disease, 5 in neuroblastoma 0.25 in soft tissue sarcoma and 0.5 in medulloblastoma. The peak incidence of cancer was in the ages between 3 to 4 years. (11.2%) and lowest was in the ages of 14 to 15 years. (0.7%). ALL was the most common cancer 47.6% and Langerhanse histiocytosis was the least common one (0.7%). The prevalence of other malignancies were NHL 9.9%, Wilms Tumor 8.6%, AML 7.9% CNS Tumors5.9%. HD 5.9%. The majority of patients were inhabitance of Rasht (47.4%). Hashtpar 7.2%, Rudsar 5.9% Langrood 5.3% and Fouman 4.6% consisted the next four cities with high rates of pediatric cancers. Amlash and Siahkal had the lowest prevalence of patients (0.7%) Conclusion: In this study pediatric malignancies were more prevalent in males and the other epidemiological characteristics were quite different from the other studies, It need further evaluation.
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Review Paper: Research | Subject: Special
Received: 2013/11/26 | Accepted: 2013/11/27 | Published: 2013/11/27

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