Volume 17, Issue 68 (1-2009)                   jour guilan uni med sci 2009, 17(68): 42-49 | Back to browse issues page

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Khalaj M, Sarokhani. M, Mahyar A, Jahan Hashemi H, Godsi F. Assessing the Refractive Errors in Beta-Thalassemia Major Patients. jour guilan uni med sci. 2009; 17 (68) :42-49
URL: http://journal.gums.ac.ir/article-1-279-en.html
University of Medical Sciences
Abstract:   (5000 Views)
Abstract Introduction: Beta-thalassemia major caused abnormalities of the eyes because of skeleton deformities, especially in the skull and long-term desferrioxamine (DFD) treatment. Objective: Assessing the refractive errors in Beta-thalassemia major patients Materials and Methods: A total of 71 thalassemia patients who referred to Qoads hospital of Qazvin, were included in this study. Thirty-seven patients (52%) were female and thirty-four patients (48%) were male seventy one persons who were referred to same Hospital for opthal examinations were randomly selected as control group. All the patients (sample and control) after filling the questionnaires underwent an ophthalmologic and optometric examination by the same optometrist. Ultimately, the data were analyzed by using Spss. Result: The mean age of patients was 16±50, 37 patients were females and 34 patients were male. Among 71 patients 142 eyes 48 cases, 96 eyes (68%) were hyperopia and 18 cases (25%) were myopia. Whereas, from 142 aged-match control group, 64 persons (90%) were myopia and 4 persons (5/6%) were hyperopias. The mean of Right and Left Axial length in thalassemia patients showed 22.52±0.34 and 22.57±0.38 and for control group showed 23.12±0.7 and 23.13±0.64. There was significant difference between two groups (p<0.05). Conclusion: The occurrence of refractive error (hyperopia) in thalassemia major patients is affected by either orbital deformity or toxicity of desferrioxamine treatment and should be taken into consideration. This study showed involvement of the Beta-thalassemia major in visual system especially in hyperopia
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Type of Study: Research | Subject: Special
Received: 2013/11/26 | Accepted: 2013/11/27 | Published: 2013/11/27

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