Volume 17, Issue 66 (7-2008)                   jour guilan uni med sci 2008, 17(66): 66-73 | Back to browse issues page

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Firouzian H, Zaieni H, Alavi S, Atrkar Roshan Z, Assali R. Lung Involvement in Early Rheumatoid Arthritis. jour guilan uni med sci. 2008; 17 (66) :66-73
URL: http://journal.gums.ac.ir/article-1-315-en.html
Imam Reza Hospital
Abstract:   (5851 Views)
Abstract Introduction: Regarding to frequency of prevalence of (RA), Pulmonary involvement is a common and serious complication of rheumatoid arthritis this study was performed. Objectives: Determine the prevalence of pulmonary disease in onset of rheumatoid arthritis base on history, physical examination, radiographic and pulmonary function test. Material and Methods: 52 patients (43 women, 9 men) fulfilling the ACR (American college of Rheumatology) criteria for RA (Rheumatoid arthritis) were consecutively assessed in a cross sectional study. Detailed medical (including respiratory symptoms and the disease activity symptoms) and drug and occupational histories were obtained. All patients underwent a complete pulmonary and rheumatologic examination and conventional chest radiography. All patients underwent PFT that comprised spirometry and body plethsmography. Data were analyzed by SPSS software. Results: Their mean age was 45.8± 11.1 years (range: 21-78) and the duration of the disease was less than 6 months. Rheumatoid factor was positive in 76.9%. All patients were nonsmoker. Base on history: cough in 7.7%, dyspnea in 17.3% and wheezing in 1.9% was detected. Physical examination findings showed expiration wheezing (5.8%) and decreasing breath sound (1.9%), Chest X-ray was abnormal in 51/9% (Interstitial opacities 50% & Air-space densities 1.9%) PFT was abnormal in 30.8% (obstructive 15.4%, restrictive 9.6%, mixed pattern 5.8%). Conclusion: This study showed a high prevalence of lung involvement in beginning of rheumatoid arthritis, so we recommend to perform diagnostic investigation of pulmonary involvement (PFT, Chest X-ray, …) in beginning of RA.
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Type of Study: Research | Subject: Special
Received: 2013/12/21 | Accepted: 2013/12/21 | Published: 2013/12/21

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