Volume 16, Issue 61 (4-2007)                   jour guilan uni med sci 2007, 16(61): 39-43 | Back to browse issues page

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Mahyar A. Survey of Antibody Titers against Recombinant Hepatitis B Vaccination in 6 Years old Children. jour guilan uni med sci. 2007; 16 (61) :39-43
URL: http://journal.gums.ac.ir/article-1-396-en.html
Abstract:   (4320 Views)
Abstract Introduction: Recognition of long-term immunogenicity of hepatitis B vaccine was very important. Objective: Determination of serum antibody titer following recombinant hepatitis B vaccination in 6 years old children. Materials and Methods: This descriptive research was performed on 40, six years old children who had referred to Ghods children hospital in Ghazvin in 2003. All of children were vaccinated by 3 doses Cuban recombinant hepatitis B vaccine in infancy periods. Measuring of serum antibody was performed by giving 0.5 ce of these children's serum, in Elysea method by statistical methods such T test and chi 2. Results: The results indicated that the antibody titer in five children(12.5%) was negative (<10m IU/ml) and in thirty five children(87.5%) was positive (>10mIU/ml). There were no significant statistical difference between the level of antibody titers with sex, BMI and birth weight. Conclusion: Negative antibody titer in 12.5% of research units indicated in the recombinant Hepatitis B vaccine didn't have full effect and further evaluation was recommended
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Type of Study: Research | Subject: Special
Received: 2014/01/1 | Accepted: 2014/01/1 | Published: 2014/01/1

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