Volume 16, Issue 61 (4-2007)                   jour guilan uni med sci 2007, 16(61): 107-111 | Back to browse issues page

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Tavanai Sani A, Khalighi A. A Case Report of Fulminant Hepatitis Due to Hepatitis A in a Child with G6PD Deficiency. jour guilan uni med sci. 2007; 16 (61) :107-111
URL: http://journal.gums.ac.ir/article-1-406-en.html
Abstract:   (4607 Views)
Abstract Introduction: Fulminant hepatitis is a massive necrosis of liver that occurs in 1-2% of symptomatic acute hepatitis. Its most common etiology is co- infection of HBV & HDV and less commonly seen after HCV infection. In pregnancy, HEV can lead to Fulminant hepatitis in up to 20% of cases and it is also described following medications, metabolic diseases like Wilson, and Post liver transplantation. One of its rare etiologies is Hepatitis A (0.14% in U.S.A) because this infection is a common benign and self limited viral disease in ages under 20. Although, if the patient suffers from underlying disease such as G6PD deficiency (that is common among Mediteranian region and has a complex duration), HAV infection can be complicated and tends to Fulminant hepatitis. Case report: In this case report, one 6 years old male child with Fulminant hepatitis has introduced who had a positive serology for HAV and at the same time a G6PD deficiency as the predisposing factor. This report suggested to search for underlying diseases (like G6PD deficiency) in all patients who have an unusual form of Hepatitis A.
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Type of Study: Research | Subject: Special
Received: 2014/01/1 | Accepted: 2014/01/1 | Published: 2014/01/1

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