Volume 13, Issue 50 (7-2004)                   JGUMS 2004, 13(50): 76-80 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kalantari S. Neonatal Screening for Congenital Hypothyroidism (CH) in Rasht. JGUMS 2004; 13 (50) :76-80
URL: http://journal.gums.ac.ir/article-1-671-en.html
Abstract:   (35701 Views)
ِAbstract Introduction: Early diagnosis and treatment of congenital hypothyroidism before 6 weeks of birth and preferably at birth, prevents brain damage. Neonatal screening for CH is carried out routinely in developed countries. Overall, the incidence of CH is 1.4000 infants in average. The incidence is higher in iodine deficient areas also more transient TSH elevation is observed in these districts. Objective: This study was conducted to clarify thyroid dysfunction in the neonates born in Rasht Alzahra Hospital, after elimination of Iodine deficiency in the province. Materials and Methods: All the newborns, up to 3000 neonates, born in one year were included in the study. TSH was measured in cord blood serum immediately after birth by IRMA method. TSH  20 mU/L was considered abnormal. Venous sampling for TSH & T4 was done on recalled patients. Neonates with T4 and TSH measurements <6.5 g/dL & >10 mU/L respectively or TSH> 30 mU/L alone were considered hypothyroid. Hypothyroid neonates were evaluated for renal and cardiac anomalies by sonography and echocardiography. Results: 62 neonates had TSH20 mU/L. The mean of cord blood TSH was 32.5 mU/L, with a range of 20-123 mU/L. in recall, only 2 cases (one girl, one boy) had elevated TSH (TSH>10mu/L) and were considered hypothyroid. None of them had clinical findings of hypothyroidism, goiter and congenital anomalies. Conclusion: With respect to the high incidence of CH and transient TSH elevation (57 cases, 1.9%), supervision on production and consumption of iodide salts via periodic screening of population for iodine deficiency and neonatal screening for CH is strongly suggested.
Full-Text [PDF 102 kb]   (4850 Downloads)    
Review Paper: Research | Subject: General
Received: 2014/07/8 | Accepted: 2014/07/8 | Published: 2014/07/8

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Guilan University of Medical Sciences

Designed & Developed by : Yektaweb