TY - JOUR T1 - Survey on the Eradication of Helicobacter Pylori Infection in Quadruple Therapy:Amoxicillin, Bismuth, Omeprazole and Clarithromycin TT - تأثیر رژیم چهار دارویی (آموکسی‌سیلین، بیسموت، امپرازول و کلاریترومایسین) در ریشه‌کنی عفونت هلیکوباکتر‌پیلوری JF - gums-med JO - gums-med VL - 23 IS - 91 UR - http://journal.gums.ac.ir/article-1-814-en.html Y1 - 2014 SP - 61 EP - 67 KW - Amoxicillin KW - Bismuth KW - Clarithromycin KW - Drug Therapy-Combination KW - Helicobacter Pylori KW - Omeprazol N2 - Introduction: Helicobacter Pylori infection is one of the most common infectious diseases.It can result in chronic gastritis, peptic and duodenal ulcers, MALT lymphoma and gastric cancer. The H-pylori infection can lead to a wide range of diseases and the cost spent on the eradication is much less than the cost spent on the treatment of complications of the infection Objective: Study the efficacy of quadruple therapy (Amoxicillin, Bismuth, Omeprazole and Clarithromycin) on the eradication of Helicobacter Pylori infection. Materials and Methods: Between March 2011 and December 2011, we conducted a Quazi- experimental study on Helicobacter pylori infectious patients in Anzali. They were included after doing an endoscopy. Eight weeks after taking four-drugs regimen, Urea Breath Test was done to check the rate of eradication. Result: The majority of the patients were females (58.7 %). The most common symptoms before the treatment were flatulence (76 %) and epigastric pain (74.9 %). The eradication rate was 89.9 %. There were significant differences in all of the symptoms while the difference between gender and eradication rate was non-significant. Conclusion: Regardless of few side effects, all symptoms of the patients were treated significantly. As the eradication rate was 89.9 %, this quadruple drug regimen was effective on the eradication of the H-pylori. Conflict of interest: non declared M3 ER -