2024-03-29T02:01:24+03:30 http://journal.gums.ac.ir/browse.php?mag_id=72&slc_lang=fa&sid=1
72-1760 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Evaluation of Genomic Polymorphism of Candida Albicans, Isolated from the Patients with Vaginitis by RAPD-PCR Method F Mofidian K Amini M J Kazemy Abstract Introduction: Candida albicans are human selective symbiosis, mainly located in the gastrointestinal tract. This group of fungi is pathogenic where host resistance reduces to local or systemic infection. Bacteria are the most common cause of vaginitis, but candida albicans are the second leading cause of such infections. Candida albicans are responsible for 70-90% of the fungal infections in the vaginal area. objective: To study the genomic polymorphism of Candida albicans isolated from women with vaginitis using RAPD-PCR method. Materials and Methods:This cross-sectional study was designed and implemented by descriptive-analytic method. In this research, 60 samples of 30 vaginal samples from Shariati Hospital (Tehran) and 30 samples from Kerman Women's Hospital were collected by gynecologist and obstetrician. Using a sterile loop, various species yeasts were cultured on a differential chromatographed medium of Candida agar. Differentiation of subspecies and study of the possible relationship between specific strains and clinical forms was done. Typing of Albicans isolates was also done using RAPD-PCR method with random primers. Results: Increased non-albicans and resistance to drugs not only in different parts of Iran but also in the world have been reported. In this study, based on the results of culture and direct experiment, 60 people were found to be infected with candida volvaginitis infection in two provinces of Kerman and Tehran, which were genetically similar and different in 14 clusters. Some clusters have repeated strains indicating similarity to genomic strains. Conclusion: There are several methods for genomic fingerprinting of different types of clinical isolates of candida albicans, using Pulsed Field Gel Electrophoresis (Pulsed Field Gel Electrophoresis) technique, fingerprinting methods based on ribotaiping, and fingerprinting methods based on PCR for epidemiological outbreaks are useful. Conflict of interest: non declared Candida Albicans polymorphism Random Amplified Polymorphic DNA Technique Vaginitis 2019 2 01 1 10 http://journal.gums.ac.ir/article-1-1760-en.pdf
72-1759 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Individual Consequences of an Organizational Trauma in a Health Care Provider Unit S A Ebrahimi S M M Baki Hashemi Abstract Introduction: Organizational trauma theory is one of the latest topics in the organizational field which examines the impact of mental and emotional modes on the organization,  individual and organizational performance. Any organization with specific features is subject to a different organizational trauma. Extracting this kind of trauma is a constructive help in managing the organization more correctly. Objective: To examine the individual consequences of an organizational trauma in a health service provider unit. Materials and Methods: This is an applied and descriptive study and has been conducted by survey method. The statistical population of the study consisted of 200 personnel of a public health service provider in the northern region of Iran. Random sampling method was used. The questionnaire based on Likert spectrum was used in order to collect data. Structural equation modeling was used to analyze research data through statistical tests. Results: In the first step it was determined the investigated organization is traumatized. Then, the research hypotheses on the effect of traumatic organization on the variables examined were confirmed. Conclusion: In the research, it was revealed that the organization under investigation in the dimensions of existence, depression, fear and anger in the staff section the outbreak of stress and anxiety in the organization section, Intra-organizational relationships, trauma is struck. And in the dimension of organizational identity reduction, there is a short distance with the range of trauma. Conflict of interest: non declared Efficiency Organizational Health personnel Personnel Management Organizations Resilience Psychological 2019 2 01 11 24 http://journal.gums.ac.ir/article-1-1759-en.pdf
72-1753 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Associations of Family Function and Socioeconomic Status with Vulnerability to Addiction: The Mediating Role of Spirituality Intelligence B Shalchi Z Sohrabi SH Shoresh hatampour Abstract Introduction: According to literature, eligible family and socio-economic status with spiritual acumen can decrease the vulnerability of individuals to substance use. Objective: The aim of this research was to investigate the mediating role of spirituality intelligence in relationships of family function and socioeconomic status with vulnerability to addiction. Materials and Methods: This study was a kind of a correlational one which has been conducted on a sample of 495 students in Payame Noor University of Urmia. The Students were taken apart in research by answering the Identifying People in Risk of Addiction Questionnaire, Family Assessment Device, socioeconomic status questionnaire and Spiritual Intelligence Self-Report Inventory. The Data were analyzed using descriptive statistics, correlation matrix and Structural Equation Model Results: For evaluating adequacy and goodness of fitness of the model, RMR, RMSEA, CFI, AGFI, GFI, X2, X2/df, indices were computed. Findings supported the goodness of fitness of suggested model in this study Conclusion: We can conclude that family function and socioeconomic status by mediating role of spirituality intelligence dimensions strongly predict the vulnerability to addiction in university students. On the basis of such findings, we can reinforce the family functions and spirituality potential of individuals, and consequently enhance their resiliency to substance use disorder. Conflict of interest: non declared Family Intelligence Narcotic Addiction Spirituality 2019 2 01 25 34 http://journal.gums.ac.ir/article-1-1753-en.pdf
72-1755 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Bioequiwin: Design of a Bioequivalence Software E Aboutaleb S Manoochehri Abstract Introduction: Bioequivalence studies are the most important way of evaluating the quality and efficacy of pharmaceutical formulations. In a bioequivalence study, the rate and extent of drug absorption into the general circulation is measured and the pharmacokinetic parameters should be calculated and statistically evaluated for the reference and test products. Pharmacokinetic parameters such as Cmax, Tmax, AUC, and Kel are the principles to determine the rate extent of drug entry into the bloodstream, which are achieved from complex calculations over the initial blood concentrations. Complex pharmacokinetic and statistical calculations parameters from these studies are the most important challenges in these types of studies which leads to an interpretation of the wrong results. In the present study, a software was designed for this type of calculations. The user interface is easy for researchers and may be used without engaging the operator in pharmacokinetic and statistical processes. Objective: Design a domestic, easy and user-friendly software to help implement biequivalence studies. Materials and Methods: Microsoft Visual Basic 14 was utilized in order to create the software and its main scientific reference guide was the FDA Guidance for Industry for Bioavailability and Bioequivalence Studies. Conclusion: The present software can be used as a complete package for bioequivalence studies. Conflict of interest: non declared Bioequiwin Software Bioequivalence 2019 2 01 35 44 http://journal.gums.ac.ir/article-1-1755-en.pdf
72-1756 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Role of Anger and Health Locus of Control in Predicting Adjustment to Cancer M Jafari S Basharpoor N Amiri Abstract Introduction: Cancer is a global problem and the third cause of death among Iranian people. Considering the chronicity of cancer, adjustment to it is one of the effective factors on the outcomes of the treatment. Objective: In this study, the role of anger and health locus of control predicting adjustment in cancer patients is examined. Materials and Methods: This work is a descriptive - correlational study. All the cancer patients referred to Imam Reza and Ghazi Tabatabaei hospitals for medical care at Tabriz, Iranin Summer and Fall 2016 comprised the statistical population of this study. The sample included 100 patients which had been selected via purposive sampling method. They were asked to respond to questionnaires of demographic information, the Mini-Mental Adjustment to Cancer, the Multidimensiinal Inventory and the Multidimensional Health Locus of Control (MHLC) scale. The collected data were analyzed by SPSS20 using tests of Pearson correlation and multivariate regression.  Results: Pearson correlation test indicated that the adjustment to cancer had a negative correlation with the anger arousal (r= -0.51; P<0.001), the rage contentious situations (r= -0.24; P<0.05), the hostile attitude (r= -0.41; P<0.001) and anger in (r = -0.43; P<0.001) and positive correlation with the internal locus of control (r= 0.25; P<0.05). The results of regression analysis revealed that 34% of the total variance of adjustment to cancer was explained by anger including anger arousal and anger in, and 10% of it was explained by internal locus of control. Conclusion: The results indicated that the anger including anger arousal and anger in plays a considerable role in adjustment to cancer. According to the findings, health locus of control does not have a considerable role in predicting adjustment to cancer. Conflict of interest: not declared Anger- Neoplasms-Neoplasms 2019 2 01 45 53 http://journal.gums.ac.ir/article-1-1756-en.pdf
72-1757 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 The Comparison of Social Adjustment, Stress and Resiliency in Women with Premenstrual Syndrome and Normal MM Pasandideh H Atashzamzam A Saberi Abstract Introduction: Premenstrual syndrome in women generally affects mental health, and stresses and consequences of this make it difficult for a person to adapt and resonate. The purpose of this study was to compare the dimensions of social adjustment, stress and resiliency in women with premenstrual syndrome and women without this syndrome. Objective: The comparison of social adjustment, stress and resiliency in women with premenstrual syndrome and normal. Materials and Methods: This is a comparative study conducted on a statistical population consisting of women with premenstrual syndrome and women without this syndrome in Lahijan city in 1396. PMS symptoms questionnaire was used to select PMs. Therefore, the sample included 150 patients (75 women with syndrome and 75 non-infected women) who were selected by available sampling method and were selected using social adjustment (SAS), perceived stress and persistence of Conner and David Sven was examined. For data analysis, variance analysis was used. Results: The results of multivariate analysis of variance showed that there is a significant difference in the dimensions of husband's adjustment and compatibility as a member of family unit, resilience and perceived stress among women with premenstrual syndrome and non-infected counterparts.. Conclusion: The premenstrual syndrome and the severity of its symptoms are affected by the stress and resilience of women, which affects their compatibility in normal conditions of life. Therefore, by identifying the effects of PMS on daily life and attempting to reduce its negative effects, the field for increasing the compatibility and dimensions of women's mental health can be provided. Conflict of interest: non declared premenstrual Syndrome Resilience Psychological Social Adjustment Stress 2019 2 01 54 61 http://journal.gums.ac.ir/article-1-1757-en.pdf
72-1758 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 The Effectiveness of Group Schema Therapy on Behavioral Activation/ Inhibition Systems and Cognitive Emotion Regulation in Female Students With Anxiety Symptoms M Rahbar Taramsari P Keshavarz A Abolghasemi E Rahbar Karbasdehi F Rahbar Karbasdehi Abstract Introduction: Students with anxiety symptoms are faced with various physical and psychological stressful factors which ‎leads to decreasing quality of life. Considering the relationship between behavioral activation/ inhibition systems and cognitive emotion regulation with early maladaptive schemas, one of the methods capable of assisting the students with anxiety symptoms is schema therapy. Objective: To determine the effectiveness of group schema therapy on behavioral activation/ inhibition systems and cognitive emotion regulation in female students with anxiety symptoms. Materials and Methods: This study is an experimental with pre-test/post-test and a control group. The sample consisted of 28 guidance school students with anxiety symptoms in Rasht city in the school year 2016-2017. Based on the Beck Anxiety Inventory(1990) and the diagnostic and statistical manual of mental disorders(2013) criteria, the study participants were identified and assigned to two experimental and control groups. To collect data, Behavioral Activation/ Inhibition Scale(2005) and Cognitive Emotion Regulation Questionnaire(2001) were used before and after treatment. 10 sessions of Young schema therapy were implemented for experimental group. Results: The results of multivariate analysis of covariance showed that group schema therapy improved behavioral activation/ inhibition systems and cognitive emotion regulation in the students with anxiety symptoms (P<0.001). Conclusion: According to the findings of the research, schema therapy can be used to cope with students' anxiety symptoms and improve cognitive emotional regulation. Conflict of interest: non declared Anxiety Emotions Inhibition Social Control Formal 2019 2 01 62 70 http://journal.gums.ac.ir/article-1-1758-en.pdf
72-1782 2024-03-29 10.1002
Journal of Guilan University of Medical Sciences JGUMS 2383-4307 2423-4818 10.32598 2019 27 108 Database/ Guilan University of Modical Sciences/ Periodicals/ Writing 2019 2 01 71 77 http://journal.gums.ac.ir/article-1-1782-en.pdf