Volume 24, Issue 96 (1-2016)                   JGUMS 2016, 24(96): 87-96 | Back to browse issues page

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Sharifi- Zahabi E, Entezari M, Maracy M. Effects of Soy Flour Enriched Bread Consumption on Plasma Lipid Profile and its Association with ApoE Genotype in Overweight and Obese Women. JGUMS 2016; 24 (96) :87-96
URL: http://journal.gums.ac.ir/article-1-1109-en.html
1- Isfahan University of Medical Sciences , entezari@hlth.mui.ac.ir
Abstract:   (5856 Views)

Abstract

Introduction: Soy products consumption may have favorable effects on cardiovascular diseases risk factors. These effects may be associated with the polymorphism in Apo E gene.

Objective: To examine the effects of consumption of soy flour enriched bread on plasma lipids and its association with ApoE genotype in overweight and obese women.

Materials and Methods: In this randomized cross-sectional clinical trial, 30 overweight and obese women received a mild weight loss diet and then, randomly assigned to a regular diet and a soy bread diet, each for 6 weeks and a washout period for 20-d. In the soy bread diet group, 120 gr of soy flour enriched bread was replaced by equal amount of usual bread intake.  

Results: No significant effect of soy bread on lipid profile was observed when comparing the two groups (P <0.05). Evaluation of the effects of the two ApoE groups E2 (&epsilon 2/ &epsilon2) and E3 (&epsilon3/ &epsilon3 or &epsilon2/ &epsilon3) showed a significant effect of soy bread on TG in E2 group, compared to E3 group (P=0.02).

Conclusion: Soy bread consumption has favorable effects on serum TG of overweight and obese women with &epsilon2 allele.

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Review Paper: Research | Subject: Special
Received: 2016/01/11 | Accepted: 2016/01/11 | Published: 2016/01/11

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