Volume 7, Issue 25 And 26 (4-1998)
JGUMS 1998, 7(25 And 26): 23-29 |
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Noyan Ashraf M, Behzadi G, Glanbari A, Gazour R, Ansar M. The Hypothalamic Suprachiasmatic Nucleus of Rat:A Golgi and
Tyrosine Hydroxylase Immunohistochemical Study
. JGUMS 1998; 7 (25 and 26) :23-29
URL: http://journal.gums.ac.ir/article-1-1951-en.html
URL: http://journal.gums.ac.ir/article-1-1951-en.html
Abstract: (3302 Views)
ABSTRACT
The hypothalamic suprachiasmatic nuclei(SCN),located in the anterior basal forebrain are responsible for important biological rhythms in physiology and behaviour in mammals. Mechanisms underlying these rhythm production is one of the most exciting fields in biology and medicine.One possible way to achieve this goal, is to find out more details about the microanatomy of the nuclei and their connections with other regions in the central nervous system. In this study ,morphology of the neurons located in the SCN were determined using a Golgi impregnation method. An immunohistochemical technique for catecholamine synthesis rate limiting enzyme,i.e.tyrosine hydroxylase(TH),was also used to study the morohology and distribution of TH positive neurons and fibers in the SCN and the periSCN region of the brain of young male albino rats. Our results according to golgi staining showed that there are at least 5 morphologically discussed neurons in the SCN .Immunoreactive TH-positive neurons and fibers were also detected in and around the nuclei. Possible importance of different neuronal subtypes for function of the SCN were disscused and it was also emphasized that the adult SCN is under the influence of the catecholaminergic system that could affect its pacemaker function
The hypothalamic suprachiasmatic nuclei(SCN),located in the anterior basal forebrain are responsible for important biological rhythms in physiology and behaviour in mammals. Mechanisms underlying these rhythm production is one of the most exciting fields in biology and medicine.One possible way to achieve this goal, is to find out more details about the microanatomy of the nuclei and their connections with other regions in the central nervous system. In this study ,morphology of the neurons located in the SCN were determined using a Golgi impregnation method. An immunohistochemical technique for catecholamine synthesis rate limiting enzyme,i.e.tyrosine hydroxylase(TH),was also used to study the morohology and distribution of TH positive neurons and fibers in the SCN and the periSCN region of the brain of young male albino rats. Our results according to golgi staining showed that there are at least 5 morphologically discussed neurons in the SCN .Immunoreactive TH-positive neurons and fibers were also detected in and around the nuclei. Possible importance of different neuronal subtypes for function of the SCN were disscused and it was also emphasized that the adult SCN is under the influence of the catecholaminergic system that could affect its pacemaker function
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Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
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