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Abstract Introduction: Fatigue and hostility can be influence quality of life in patients with coronary artery disease. Objective: Investigation the relationship of fatigue and hostility with quality of life in patients with coronary artery disease. Materials and Methods: The samples consisted of 60 coronary heart disease patients which were selected among all coronary artery disease persons who had referred to Heshmat Hospital in Rasht. For gathering data were used. Choreic Fatigue Scale, Hostility Scale and Health survey. Data was analysed by using Pearson correlation coefficient and multiple regression analyses. Results: The results of Pearson correlation coefficient showed that fatigue (r=-.64) and hostility (r= -.25) are related to quality of life (P<0.05). The results of multiple regression showed that physical fatigue, is the best significant contribute in prediction of quality of life in patients with coronary artery disease. Conclusion: These results are in keeping with findings from other studies and indicated that the role of fatigue and hostility in quality of life in patients with coronary artery disease.

Keywords: Coronary Arteriosclerosis, Fatigue, Hostility, Quality of Life

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