Volume 31, Issue 2 (6-2022)                   J Guil Uni Med Sci 2022, 31(2): 166-179 | Back to browse issues page

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Saadat S, Saberi A. Environmental Risk Factors in Multiple Sclerosis: A Narrative Review. J Guil Uni Med Sci 2022; 31 (2) :166-179
URL: http://journal.gums.ac.ir/article-1-2382-en.html
1- Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran.
2- Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. , alia.saberi1@gmail.com
Abstract:   (448 Views)
Background Multiple sclerosis (MS) is one of the chronic autoimmune diseases and a progressive disease of the central nervous system that have unknown causes.
Objective This study aims to review the environmental risk factors of MS.
Methods In this review study, a search was conducted in databases such as PubMed, Scopus, ScienceDirect, Google Scholar and MagIran on related studies published in Persian and English from 2000 to 2021 using the keywords: Multiple Sclerosis, MS, Environmental risk factors, and Epidemiology.
Results The studies showed that MS is an autoimmune disease with unknown genetic backgrounds. The age of 20-40 years, female gender, distance from the equator, migration, Epstein-Barr virus infection, smoking, air pollution, vitamin D deficiency, alcohol and coffee consumption, circadian disruption, and psychological factors are the environmental risk factors of MS.
Conclusion Given the environmental risk factors of MS, their control is potentially helpful in preventing the disease and its rapid progression. It is necessary for health care providers to pay attention to these risk factors.
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Type of Study: Research | Subject: Special
Received: 2021/07/9 | Accepted: 2022/05/22 | Published: 2022/07/1

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