Volume 31, Issue 4 (12-2022)                   J Guil Uni Med Sci 2022, 31(4): 328-337 | Back to browse issues page

Research code: 96082002
Ethics code: IR.GUMS.REC.1396.430

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hashemian H, Sanati F. Comparing the Mean Platelet Volume and the Neutrophil-to-Lymphocyte Ratio in Children With Bacterial Pneumonia Associated With or Without Pleural Empyema. J Guil Uni Med Sci 2022; 31 (4) :328-337
URL: http://journal.gums.ac.ir/article-1-2403-en.html
1- Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. , hashemian@gums.ac.ir
2- Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Abstract:   (160 Views)
Background Pneumonia is one of the severe infections in children, and empyema is one of its essential complications which causes more risk in affected children. Therefore, its early diagnosis is of great importance.
Objective This study aims to compare the value of two inflammatory markers including mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR) in children with pneumonia associated with and without pleural empyema.
Methods This study was conducted on the data of 128 children aged 3 months to 14 years with bacterial pneumonia associated with pleural empyema and 128 children without pleural empyema. The MPV and NLR values and the patients’ demographic and clinical characteristics were analyzed in SPSS software version 18 software. The confidence interval for the area under the ROC curve was calculated using binomial exact method. The significance level was set at 0.05.
Results Of 256 children, 42.2% were girls, and most of children had ages <3 years (35.2%). Children with empyema had significantly higher NLR, platelet count, and MPV than children without empyema (P=0.040, 0.005, and 0.021, respectively). The MPV (P=0.020) and NLR (P=0.039) were significant predictors of empyema.
Conclusion The use of NLR and MPV may be useful in the early diagnosis of empyema in children with pneumonia.
Full-Text [PDF 3956 kb]   (40 Downloads) |   |   Full-Text (HTML)  (13 Views)  
Type of Study: Applicable | Subject: Special
Received: 2021/09/12 | Accepted: 2022/09/21 | Published: 2022/11/16

Add your comments about this article : Your username or Email:

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Journal of Guilan University of Medical Sciences

Designed & Developed by : Yektaweb