Research code: 2010/63/EU
Ethics code: IR.IAU.K.REC.1401.061
1- Department of surgery, Karaj branch, Islamic Azad University, Karaj, Iran
2- Department of clinical sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
3- Department of Radiology, Karaj branch, Islamic Azad University, Karaj, Iran.
4- Department of Physics, Karaj Branch, Islamic Azad University, Alborz, Iran
Abstract: (44 Views)
Background: Low-level laser therapy is a non-invasive treatment method that enhances tendon repair by accelerating healing, offering a promising approach for improving recovery outcomes.
Objective: This study investigated the effects of low-level laser therapy on tendon injuries in a rabbit model using ultrasonography to assess the impact of treatment.
Methods: Fifteen adult male New Zealand White rabbits were obtained and randomly assigned to one control group and two laser therapy groups (650 nm and 750 nm). Ultrasonography was performed weekly over 42 days (six sessions). Following surgically induced tendon injury in the right hind limb, rabbits underwent low-level laser therapy, and tendon repair was evaluated using ultrasonography. Data were analyzed using SPSS software version 21, and a significance level of <0.05 was considered.
Results: After surgery, tendon thickness increased in all groups during weeks 2–3 and then decreased; the control group demonstrated the greatest thickness and the slowest reduction rate, while the 750 nm laser group showed the highest initial increase. A significant difference was observed between the 650 nm laser group and the other groups (P > 0.05), whereas no significant difference was found between the 750 nm laser group and the control (P = 0.321). Echogenicity and tissue uniformity improved more rapidly in the laser-treated groups and reached high-uniformity status by week five, whereas the control group exhibited a slower pattern. Overall tendon repair assessment showed that the 650 nm group had better healing scores in the first, third, and fourth weeks (P < 0.05), and both laser groups performed better than the control group, confirming a faster regenerative trend in the laser-treated groups.
Conclusion: Low-level laser therapy, particularly at the 650 nm wavelength, significantly enhances tendon healing by improving thickness, echogenicity, and echotexture more rapidly than the control group across all evaluations.
Review Paper:
Research |
Subject:
Special Received: 2025/10/26 | Accepted: 2026/02/18