Volume 16, Issue 64 (1-2008)                   JGUMS 2008, 16(64): 16-23 | Back to browse issues page

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Rahimi bashar F, Jafroodi M, Zari doost A. Survey of Cardiac Complications in Beta Thalassemia Major Patients in 10-20 Years Old . JGUMS 2008; 16 (64) :16-23
URL: http://journal.gums.ac.ir/article-1-339-en.html
1- , Frbashar@yahoo.com
Abstract:   (7235 Views)
Abstract Introduction: Thalassemia is the most common monogenic disorder in the world and cardiac complications are the most common causes of mortality of Beta Thalassemia Major Patients. Objective: Survey of relative frequency of cardiac complications including Diastolic, Systolic Dysfunctions, Arrhythmia and Pericardial Effusion in Beta Thalassemia Major Patients (10-20 years old). Material and Methods: In these descriptive study 58 beta thalassemia major patients, 10-20 years old, 32males, 26 females who had referred to Heart Clinic were studied by history, electrocardiogram and echocardiography. Holter monitoring was recommended if there were history of palpitation, abnormal electrocardiogram or antiarrhythmic therapy. Results: There were cardiac complications in 19 patients (32.8%), 15 patients were above 15 years old and 4 patients were 15 years old and less than. Cardiac patients were including 13 males (40.6%) and 6 females (23.1%). There was arrythmia in 4 patients (6.8%) including one Mobits II, one PSVT, one ventricular tachycardia and one PVC. Diastolic dysfunction was in 8 patients (13.8%). Systolic dysfunction was in 6 patients (10.3%).There wasn’t pericardial effusion. One patient was died due to heart failure. In cardiac patients ferritin average was 3247.32 1359.07ng/ml. There was correlation between serum ferritinr level with cardiac complications and age but there was not correlation with sex or arrhythmia. Conclusion: Increase of feritin level and age is effective in heart faliture in Beta thalassemia major patients.
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Review Paper: Research | Subject: Special
Received: 2013/12/24 | Accepted: 2013/12/24 | Published: 2013/12/24

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