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Abstract: (9431 Views)
Abstract Introduction: Neonatal hyperbilirubinemia is a very common problem in neonates that can lead to kernicterus and auditory disturbance. Neonatal icter is a common cause of neuro-sensory hearing loss and an important factor for children deafness. Objective Survey the relationship of neonatal icter on brain stem and auditory state of neonates that were admitted in hospitals of Rasht. Materials and Methods: In this cross sectional, research we evaluated 63 neonates with increase of indirect hyperbilirubinemia that were admitted in the hospitals of Rasht for assessment of auditory state by A.B.R (Auditory Brain Response ). The evaluated variation of A.B.R consisted of: Lack of wave, latency and inter-peak time of wave. The neonates with direct hyperbilirubinemia, preterm with LBW, asphyxia and hyperosmolarity were excluded of this study. Results: The neonates have been divided into two groups based on the level of bilirubin (12-20 mg/dl & >20 mg/dl). From 63 patients the bilirubin level of 45 (%71/4) neonates was 12-20 mg/dl and 18 (%28/5) neonates were more than 20 mg/dl. In the first group (bilirubin 12-20 mg/dl ) A.B.R changes were not seen and the auditory state of these neonates was normal, however in the second group ( bilirubin >20 mg/dl) inter-peak latency I – V was elevated in 8 (%44/4) neonates. Conclusion: Increase the level of indirect bilirubin (>20 mg/dl) caused disorder on the auditory neonatal state, of that should be prevented by exchange transfusion. So we recommend A.B.R for screening and early detection of bilirubin ototoxicity and necessary audiologic intervention in all cases of severe neonatal hyperbilirubinemia.
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Special Received: 2013/12/24 | Accepted: 2013/12/24 | Published: 2013/12/24