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Abstract Introduction: Postpartum depression is a prevalent disorder that has undesirable effects on mother and child’s health. Its prevalence is reported different in various studies. Objective: The aim of this study was to determine the prevalence of postpartum depression in mothers who delivered at Alzahra hospital in Rasht in 2004. Materials and Methods: In this cross sectional study 335 women who delivered at Alzahra hospital after signing informed consent were assessed with a demographic questionnaire including variables (age, live child number, home living, delivery type, wanted or unwanted pregnancy, history of abortion or dead child, delivery number, educational level, employment status after delivery). Samples were screened with Beck depression inventory (a standard self questionnaire and independent of any cultural bias) 2-3 weeks after delivery. For mothers who scored 16 or higher, a structural clinical interview for major depressive disease was done. The interview results were evaluated according to DSMIV-TR criteria and the results were analyzed and statistically significant difference was determined (α=0/05) Results: According to the screening examination, 61 patients had mild depression (scoring 16-230) and 6 patients suffered moderate depression (scoring 31-46). From 59 patients who referred for clinical interview, 48 had essential depression disorder based on DSMIV-TR and 43 had mild depression. There was a significant relationship between mothers’ occupation and depression (P=0.02) and between history of still birth and infant death in past with depression (P=0.02) Conclusion: The prevalence of mild depression in our study was notable. In addition to the limitations of this study, more studies with more specific screening assessment and more subjects are recommended

Keywords: postpartum depression, Beck depression inventory, structured clinical interview

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