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Abstract Introduction: Considering the side-effects of opiums and NSIADS drugs such as respiratory depression, apnea and GI effects, today it has been paid more attention to intra abdominal wall infiltration of local anesthetics for this purpose. Objective: The aim of this study is to determine the effect of intra abdominal wall infiltration with bupivacaine to reduce post operative diclofenac need in elective cesarean sections. Materials and Methods: In this double- blind, placebo-controlled trial, 60 healthy women with single term pregnancy underwent spinal anesthesia were randomized into two groups. Patients, then received a combination of 30cc of bupivacaine with 1.5cc of epinephrine as intra abdominal wall infiltration or equal volume of saline in cesarean section at the time of abdominal closure. Pain was assessed using a visual analogue scale 1, 2, 3, 4, 8 and 12 h after the operation.Also mean diclofenac consumption was assessed during 12 h after the operation. The final analysis was done with statistical tests by SPSS (P<0.05 was considered significant). Results: Mean pain scores at 1 and 2 h after the operation was significantly lower in bupivacaine group than placebo(p<0.05). Mean diclofenac consumption was lesser in bupivacaine group than placebo (p<0.05). Also the time we prescribed diclofenac in bupivacaine group was later (p<0.05). Conclusion: Intra abdominal wall infiltration with 30cc of 0.25% bupivacaine leads to less pain and less diclofenac consumption at the first hours after cesarean section.

Keywords: Bupivacaine/ Cesarean Section/ Diclofenacs/ Epinephrine/ Pain, Postoperative

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