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Abstract Introduction: One of the most common peripheral nerve entrapments is known as carpal tunnel syndrome. Nerve Conduction Velocity (NCV) study and Electrodiagnostic test is the most sensitive diagnostic for CTS which is a quantitative and independent method to patients report and its outcomes are usually equal in various patients. It showed a nerve conduction delay in 70-90 percent of patients. Objective: Comparison of nerve conduction velocity (NCV) in the forearm between normal hand and with CTS. Materials and Methods: In this prospective study, 89 patients with Clinical diagnosis of CTS patients without any underling diseases were selected among patients who referred to Poorsina electro-diagnostic clinic. Data was collected through questionnaire, clinical examination and their NCV files, and then they were analyzed by Paired-T-test and SPSS. Results: During 4 months, 89 patients with clinical and electro diagnostic of CTS were selected.48 patients (53.9%) were female and 41 patients (46.1%) were male. The ratio of female to male was 1.17%: 1.55(61.8%) of them suffered from CTS symptom in right hand. The average of (NCV) in right hand of patients was 58.11±12.10(m/s)and in left hand of them was 51.31 ± 12.56(m/s) .According to our data distribution based on Paired sample T-test for average comparison, the P-value is equal to 0.0001 which showed a significant difference between CTS forearm and the health one. This difference was from 4.74 m/s to 7.35 m/s. In the other word, it showed a 6.04 reduction in NCV related normal hand. Conclusion: Nerve Conduction Velocity decreased significantly trough CTS forearm toward health one.

Keywords: Atrophy, Carpal Tunnel Syndrome, Electrodiagnosis, Median Nerve, Neural Conduction

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* Corresponding Author Address: Poorsina Hospital, Rasht, IRAN

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