Abstract: (1718 Views)
ABSTRACT
Major Beta thalassemia is a common disease in Guilan province with about 1500 patients. These patients especially spelenctomized Considered to be at high risk of septicemia. In this report during 5 years ago two Splenectomized patients had Septicemia caused by Escherichia coli. They Presented Symptoms of fIever and chill. Treatment was effective in all cause and septicemia was not fatal in these two patients. Before admission these two patients were on regular blood transfusion and adequate desferal Injection but they all had Intravenas Infusion of desferal. Immunization with Polyvalent Pneamococeal vaccine prior to Splenectomy and Prophyloctic penicillin therapy following Splectomy decrease the incidence of Overwhelming Post Splenectomy infection (OPSI) caused by streptococcus pnemoniae. Intravenous infusion of Desferal, seems to Increase the risk of Infection.
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Special Received: 2019/03/5 | Accepted: 2019/03/5 | Published: 2019/03/5