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Abstract Introduction: Cerebrovascular events are one of the most disabling disorders in human being and we must search for some factors that impress upon extent of tissue damage and neuronal injury that lead to the prognosis of these events and the patients abilities .One of these factors is magnesium. Objective: To investigate the relationship between magnesium level and rankin disability score at first 72hrs and 1 week after ischemic stroke and change of this score in this period of time. Materials and Methods: In this cross-sectional study 67 patients suffering from ischemic stroke in the territory of right middle cerebral artery, less than 6 hours were involved. Their serum magnesium levels were measured in the first 6 hours after stroke and their RDS0 and RDS1w were recorded. Data was analyzed by Nominal Regression Method and Repeated Measure ANOVA respectively by SPSS 17. Results: Among 67 patients (61.20% was male and 38.8% was female), the mean age of them was 69.60±13.58 years old. There was reciprocal statistical correlation between serum magnesium level and RDS0 and RDS 1w. (P=0.000 and 0.002 respectively). But there was not any significant statistical correlation between the serum magnesium level and changes of RDS in this period of time (P=0.513). Conclusion: Measurement of serum magnesium level in the first hours after ischemic stroke can be a good predictor for patients abilities at the first 72 hours and 1 week after that event.

Keywords: Brain Ischemia, Cerebrovasclar Accident, Magnesium‌‌‌, Prognosis

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* Corresponding Author Address: Department of Neurology, Poursina hospital, Rasht, IRAN

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