Volume 6, Issue 22 (6-1997)
JGUMS 1997, 6(22): 14-18 |
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Mehrban, D. Clinical Evaluation of Mixed Agglutination Reaction (MAR) and Tray
Agglutination Tests in Infertile Men
. JGUMS 1997; 6 (22) :14-18
URL: http://journal.gums.ac.ir/article-1-1911-en.html
URL: http://journal.gums.ac.ir/article-1-1911-en.html
Abstract: (4955 Views)
ABSTRACT:
Of the antisperm immunoglobulins ,only antisperm surface IgA an IgGs are significant clinically because many fertile men have antisperm antibodies present in their sera. Since the necessity of one form of sperm surface antisperm test(specific)is felt in our country,and Immunobead is not popular here for its high cost,Mixed Antiglobulin Reaction test was studied in a population of infertile male patients.mean while alongside the Tray Agglutination Test (TAT),a nonspecific assay was also evaluated.
During a one year period , 29 infertile male patients were studied sequentially at Dr. Shariati Urology Clinic . The study tests were Direct MAR against IgA and igG sperm surface antigens , and serum and semen TAT tests . Results show that a single Direct MAR test is capable of evaluating immunoinfertility .Besides, an IgG MAR is enough and there is probably no need for an associated IgA MAR test. When the MAR Kit is not available ,a TAT test of both serum and semen is probably as useful as a single MAR test.
Of the antisperm immunoglobulins ,only antisperm surface IgA an IgGs are significant clinically because many fertile men have antisperm antibodies present in their sera. Since the necessity of one form of sperm surface antisperm test(specific)is felt in our country,and Immunobead is not popular here for its high cost,Mixed Antiglobulin Reaction test was studied in a population of infertile male patients.mean while alongside the Tray Agglutination Test (TAT),a nonspecific assay was also evaluated.
During a one year period , 29 infertile male patients were studied sequentially at Dr. Shariati Urology Clinic . The study tests were Direct MAR against IgA and igG sperm surface antigens , and serum and semen TAT tests . Results show that a single Direct MAR test is capable of evaluating immunoinfertility .Besides, an IgG MAR is enough and there is probably no need for an associated IgA MAR test. When the MAR Kit is not available ,a TAT test of both serum and semen is probably as useful as a single MAR test.
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Received: 2019/03/12 | Accepted: 2019/03/12 | Published: 2019/03/12
Received: 2019/03/12 | Accepted: 2019/03/12 | Published: 2019/03/12
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