Abstract: (2467 Views)
ABSTRACT
In this research, during one year, the antibacterial efficacy of Nitrofurantoin versus four species of gram-negative bacteria(Collected of UTis patients)is measured and compared by Disk-Agar Diffusion Method „Macrodiution Broth Method and Microdilution Broth Method in Ghaem University Hospital, Mashhad, Iran.
The rates of Nitrofurantoin's MIC50 & MIC90 for all of the studied bacteria except Klebsiellagenus(4 fold) by Macrodilution Broth Method were two fold similar MIC rates by Microdilution broth Method. The sensitivity rates of E.coli and Staph.saprophyticus to Nitrofurantoin were more than Enterobacter and Klebsiellaspecies.Proteus bacteria mirabilis was very resistant. In the Disk-Agar Diffusion Method,the sensitivity rates of bacteridisolated from out-patients to Nitrofurantoin were more than those in hospitalized patients.
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Special Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16