1- استادیار گروه کودکان- دانشکده پزشکی دانشگاه علوم پزشکی گیلان- بیمارستان هفده شهریور- رشت
چکیده: (1898 مشاهده)
Abstract
Cytomegalo Virus has worldwide distribution and is the most common cause of congenital infections. Acquisition of C.M.V is nearly always asympttomatic. Primary C.M.V infection acquired during pregnancy is associated with 30% to 40% risk of congenital infection. After reactivation of latent infection in mother,this rate decreases to 1% to 30%.Fetus involvement may be accompanied by severe clinical manifestation such as corioretintis, hepatosplen.megally,icterus,and IUGR or may be symptomatic only with hearing loss in the later life.Central nervous System (CNS) involvement with CMV results in encephalitis, periventricular calcification. The most common manifestation of congenital C.M.V is hearing loss. It occurs in 15% of infants with asymptomatic congenital infection and in about 5% of those with asymptomatic infection at birth. The hearing loss may be unilateral or bilateral. A 50-day-old infant with hepatosplenomegally, growth retardation,andmicrocephally was admitted to Hefdah-e-Shahrivar Hospital. Brain CT Scan showed microcephaly,calcification of periventricular areas. In the lab tests on the infants,C.M.V, titer 1/128 positive ,and on mother's C.M.V,titer 1/64 positive was found.
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تخصصي دریافت: 1397/12/25 | پذیرش: 1397/12/25 | انتشار: 1397/12/25