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1- Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan 98135-674, Iran.
Abstract: (62 Views)
Background: In this study, novel nanocomposites based on strong interactions between carbon nanotubes (CNTs) and suitable polymers are introduced and investigated for the development of electrochemical glucose biosensors. Carbon nanotubes, as a material with outstanding electrical and mechanical properties and high specific surface area, play a key role in improving the sensitivity and selectivity of sensors.
Objective: The purpose of this article is to provide a comprehensive and critical review of the historical trends and key developments in the application of nanocomposites for the fabrication of glucose measurement sensors. This research aims to identify important milestones, challenges ahead, and future opportunities in this field by analyzing past scientific papers and achievements.
Methods: In this paper, an extensive study of electrochemical glucose biosensors modified with nanocomposites based on carbon nanotubes and conductive polymers has been conducted. In this regard, a wide range of polymers including paraphenyldiamine, polypyrrole, polyaniline, polyacrylonitrile, polyvinyl ferrocene, osmium polymer and polyethylene glycol have been reported. In addition, the effect of surface modification of carbon nanotubes with different polymers on the sensitivity and detection range of glucose sensors has also been investigated.
Results: Cyclic voltammetry results obtained for each of the nanocomposites indicate a significant effect of the polymer type on the electrochemical behavior of the sensors. The electrochemical glucose biosensors based on these nanocomposites exhibit outstanding features including high sensitivity, low detection limit, fast response, long-term stability and good selectivity against other interfering substances.
Conclusion: The results show that the nanocomposites based on carbon nanotubes and polymeric materials have great potentials for application in glucose detection in biological samples and development of a new generation of biosensors. In the future, it is expected that research on smart and biocompatible nanocomposites will focus on the development of glucose sensors that continuously and non-invasively monitor glucose levels. These advances can contribute to better diabetes management and improve the quality of life of patients.
Objective: The purpose of this article is to provide a comprehensive and critical review of the historical trends and key developments in the application of nanocomposites for the fabrication of glucose measurement sensors. This research aims to identify important milestones, challenges ahead, and future opportunities in this field by analyzing past scientific papers and achievements.
Methods: In this paper, an extensive study of electrochemical glucose biosensors modified with nanocomposites based on carbon nanotubes and conductive polymers has been conducted. In this regard, a wide range of polymers including paraphenyldiamine, polypyrrole, polyaniline, polyacrylonitrile, polyvinyl ferrocene, osmium polymer and polyethylene glycol have been reported. In addition, the effect of surface modification of carbon nanotubes with different polymers on the sensitivity and detection range of glucose sensors has also been investigated.
Results: Cyclic voltammetry results obtained for each of the nanocomposites indicate a significant effect of the polymer type on the electrochemical behavior of the sensors. The electrochemical glucose biosensors based on these nanocomposites exhibit outstanding features including high sensitivity, low detection limit, fast response, long-term stability and good selectivity against other interfering substances.
Conclusion: The results show that the nanocomposites based on carbon nanotubes and polymeric materials have great potentials for application in glucose detection in biological samples and development of a new generation of biosensors. In the future, it is expected that research on smart and biocompatible nanocomposites will focus on the development of glucose sensors that continuously and non-invasively monitor glucose levels. These advances can contribute to better diabetes management and improve the quality of life of patients.
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