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Abstract Introduction: Contact eczema is a common inflammatory skin disease different materials with irritant and allergic mechanisms can produce this disease. Although history and physical examination are important in diagnosis of allergen, because of extent of several factors, environmental allergens, were not simply recognized. Patch test is an important diagnostic tool to confirm allergic contact dermatitis and can reduce mistake of clinical diagnoses. Objective: Determine frequency of dermatic allergens in patients with contact or atopic dermatitis who were referred to Razi hospital in Rasht. Materials and Methods: In a descriptive cross sectional study during 22 months, 100 patients with clinical diagnoses of contact and atopic dermatitis who referred to Razi hospital patch tested with European standard series containing 24 allergens. Their reactions were evaluated after 24, 48 and 72 hours after application of patch test. Data was collected and were analyzed by SPSS. (P<0.05 was considered significant). Results: Among 100 patients, positive patch test was seen in 36% whic mean age of them was (30.67) years (SD=10.85). The most common involved location was hand (86%) and most common allergens were Nickel sulfate (20%) and potassium dichromate (9%). In this study 6(25%) of all allergens showed positive reaction. Conclusion: Nickel Sulfate and Potassium Dichromate were the most common contact allergens in our study.

Keywords: Allergens, Dermatitis Atopic, Dermatitis Contact, Skin Tests

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