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Abstract Introduction: Nasal polyps are mucosal sac which contain edema, fibrian tissue, vessels, inflammatory cell and glands which origin from paranasal sinuses and nasal mucosa and is one of the most common benign nasal mass. Objective: Determine the relative frequency of some associated factors in patient with nasal polyp who operated at Amir- Al- Momenin hospital, Rasht. Materials and Methods: This is a analytical- descriptive study which files of patients with nasal polyps who underwent polypectomy at Amir-Al-Momenin hospital during 2003-4 were collected. Variables including age, gender, history of previous polypectomy, smoking, blood group, serum eosinophilia, bilateral polyp, presence of polyp in the other side, presence of asthma, penicillin allergy, aspirin intolerance, diabetes and atopy were studied. Results: Put of 102 patients with nasal polyps 43% were female and 57% were male. More than 50% of patients were in 10-19 and 20-29 years age group. Only 18.6% of them had a history of previous polypectomy.57% of them had bilateral polyps and 42.2% had unilateral ones. Incidence of asthma, aspirin intolerance, diabetes, atopy and penicillin intolerance in these patients were 6.8%, 1.9%, 8.8%, 9.7% and 0.9%. 14.7% of patients were smoker. Eosinophilia was seen in 11.7% of the patient. Conclusion: Asthma, aspirin intolerance, penicillin allergy are seen with lower frequency than other reports so researcher advised to perform more study to determine the prevalence of associated factors with nasal polyps in population.

Keywords: Aspirin, Asthma, Diabetes Mellitus, Nasal Polyp, Penicillins

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