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Abstract Introduction: Fetomaternal circulatory communication limited liberal drug administration during general anesthesia for cesarean section surgery. This might be the cause of light anesthesia in early period of cesarean section and might induced pain and hemodynamic instability. Objective: Survey the effect of low dose of ketamine on homodynamic stability of scheduled patients for elective cesarean section under general anesthesia. Materials and Methods: This randomized double blinded clinical trial was performed on two equal groups including sixty 22-38 years old healthy pregnant women who scheduled for elective cesarean section in Vali-Asr hospital during 1/1/82 till 1/1/83. Anesthesia was induced with standard dose of sodium thiopental and suxamethonium and was maintained with N2O/O2gas mixture (50/50) plus 0.5 Mac halothane in both control and ketamine groups. In ketamine group, 2 minutes before induction 0.3 mg/kg ketamine, administered intravenously. The homodynamic parameters were controlled and recorded any 3 minutes in all patients until childbirth. Results: Homodynamic parameters increased significantly after skin incision until childbirth in control group. In ketamine group there was more stable homodynamic parameters(HR 119.9±18.8 Vs 99.28±11.5, sys BP 115± 64 Vs 109.05±9.3 and p<0.05). Conclusion: Preinduction administration of minimal dose of ketamine might produced more stable homodynamic parameters for cesarean parturient and prevented significant changes in homodynamic parameters that is beyond of clinical effect of this dose of ketamine,

Keywords: Anesthesia-Obstetrical, cesarean Section, Homodynamic Processes, Ketamine

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