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Abstract Introduction: The incidence of tuberculosis among patients with chronic renal disorders and under hemodialysis is sixteen times more as compared to other individuals of the society and the findings of tuberculin skin test in this group were negative in 30-40% of cases. To ascertain the immunity status of the above patients is helpful in analyzing the status of tuberculosis infection. Objective: This research has been undertaken to evaluate the status of tuberculin test and the phenomenon of remembering as well as to evaluate the skin anergy among the patients of chronic hemodialysis. Materials and Methods: The method of research is descriptive and its data collection tool was interview and observation. Forty-three hemodialysis patients from Taleghani and Modares hospitals were subjected to tuberculin skin test and anergy. Skin test with the use of tetanus and diphtheria toxoid solution was carried out on the hand without fistula within a 10 CM distance. The result was announced after 48-72 hours. Those patients whose tuberculin skin test was less than 10 mm were subjected once again to PPD. Results: The average age of the patients under study was 56.6± 5.7. The time of dialysis was 54.2 ± 67.1 months and the instances of dialysis were 2.9 ± 0.3 times per week. First PPD induration was 7.1 ± 4 and 16.3 % of test findings were negative (<5 mm) and 53.5 % had induration measurement of 5- 10 mm and 30.2 % had positive result of more than 10 mm. There was a weak correlation between the findings of first PPD and age, which was statistically insignificant. There was not significant correlation between the findings of first PPD and tuberculosis precedence. There was a weak correlation between the time of dialysis and the first time PPD measurement, which was statistically insignificant. Induration measurement of anergy test was 3.9 ± 2.8 the result of this test was negative (<2 mm) in 18.6% of the patients. 83.3% of the patients with the result of less than 10 mm on the first PPD test were positive on anergy test, 28.6 % of patients had negative results for both tests of anergy and first PPD. The indurations balance of second PPD was 7.4 ± 2.8 mm and 2 patients (4.6 %) out of the total patients had result of less than 5 mm on first and second tuberculin test and showed the result of less than 2 mm on the anergy test. Conclusion: In attention to 14% of cases with negative results on anergy test who showed positive result on tuberculin test, it’s suggested that PPD and Booster tests in combination with anergy tests can be better than using tuberculosis screening in hemodialysis patients.

Keywords: Ridney Failure-Chronic, Tuberculin Test, Tuberculosis

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