Abstract
Introduction: Soy products consumption may have favorable effects on cardiovascular diseases risk factors. These effects may be associated with the polymorphism in Apo E gene.
Objective: To examine the effects of consumption of soy flour enriched bread on plasma lipids and its association with ApoE genotype in overweight and obese women.
Materials and Methods: In this randomized cross-sectional clinical trial, 30 overweight and obese women received a mild weight loss diet and then, randomly assigned to a regular diet and a soy bread diet, each for 6 weeks and a washout period for 20-d. In the soy bread diet group, 120 gr of soy flour enriched bread was replaced by equal amount of usual bread intake.
Results: No significant effect of soy bread on lipid profile was observed when comparing the two groups (P <0.05). Evaluation of the effects of the two ApoE groups E2 (&epsilon 2/ &epsilon2) and E3 (&epsilon3/ &epsilon3 or &epsilon2/ &epsilon3) showed a significant effect of soy bread on TG in E2 group, compared to E3 group (P=0.02).
Conclusion: Soy bread consumption has favorable effects on serum TG of overweight and obese women with &epsilon2 allele.
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |