Volume 33, Issue 2 (In-Press 2024)
JGUMS 2024, 33(2): 0-0 |
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Research code: 400068
Ethics code: IR.KUMS.REC.1399.248
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Shokri B, Alimohammadi E. Factors associated with poor clinical outcomes of children with moderate to severe traumatic brain injury: a retrospective observational study. JGUMS 2024; 33 (2)
URL: http://journal.gums.ac.ir/article-1-2622-en.html
URL: http://journal.gums.ac.ir/article-1-2622-en.html
1- Clinical Research Development Center, Taleghani and Imam Ali Hospitals, Kermanshah University of Medical Sciences, Kermanshah,Iran , bita.shokri@kums.ac.ir
2- Department of Neurosurgery Kermanshah University of Medical Sciences, Kermanshah, Iran
2- Department of Neurosurgery Kermanshah University of Medical Sciences, Kermanshah, Iran
Abstract: (636 Views)
Background: Traumatic brain injury (TBI) is a leading cause of mortality and disability in pediatric patients. Predicting clinical outcomes following TBI is essential for providing appropriate treatment and improving patient care.
Objective: This retrospective study aimed to investigate the factors associated with clinical outcomes in children with moderate to severe TBI.
Methods: We evaluated the clinical data of 374 children with TBI who received treatment at our center between May 2014 and May 2021. Clinical, laboratory, and radiographic data were extracted and analyzed. Clinical outcomes were assessed using the Glasgow Outcome Scale (GOS). The patients were divided into two groups: those with favorable clinical outcomes (GOS 4 and 5) and those with poor clinical outcomes (GOS 1, 2, and 3). Logistic regression analysis was performed to evaluate the relationship between different variables and clinical outcomes.
Results: A total of 374 children with moderate to severe TBI were included in the study, consisting of 197 (52.7%) boys and 177 (47.3%) girls. The mean age at the time of trauma was 7.37 ± 3.11 years. According to the logistic regression model, the Glasgow Coma Score (OR, 3.22; 95% CI: 1.78-5.24; P < 0.001), pupillary response to light (OR, 1.97; 95% CI: 1.34-2.99; P = 0.024), and Rotterdam CT score (OR, 2.61; 95% CI: 1.72-4.13; P = 0.020) were significantly associated with clinical outcomes in children with moderate to severe TBI.
Conclusion: This study's findings indicate that the Glasgow Coma Score, pupillary response to light, and Rotterdam CT score may serve as indicators of poor clinical outcomes in children with moderate to severe TBI. These results can be utilized to enhance the management and care provided to these patients.
Objective: This retrospective study aimed to investigate the factors associated with clinical outcomes in children with moderate to severe TBI.
Methods: We evaluated the clinical data of 374 children with TBI who received treatment at our center between May 2014 and May 2021. Clinical, laboratory, and radiographic data were extracted and analyzed. Clinical outcomes were assessed using the Glasgow Outcome Scale (GOS). The patients were divided into two groups: those with favorable clinical outcomes (GOS 4 and 5) and those with poor clinical outcomes (GOS 1, 2, and 3). Logistic regression analysis was performed to evaluate the relationship between different variables and clinical outcomes.
Results: A total of 374 children with moderate to severe TBI were included in the study, consisting of 197 (52.7%) boys and 177 (47.3%) girls. The mean age at the time of trauma was 7.37 ± 3.11 years. According to the logistic regression model, the Glasgow Coma Score (OR, 3.22; 95% CI: 1.78-5.24; P < 0.001), pupillary response to light (OR, 1.97; 95% CI: 1.34-2.99; P = 0.024), and Rotterdam CT score (OR, 2.61; 95% CI: 1.72-4.13; P = 0.020) were significantly associated with clinical outcomes in children with moderate to severe TBI.
Conclusion: This study's findings indicate that the Glasgow Coma Score, pupillary response to light, and Rotterdam CT score may serve as indicators of poor clinical outcomes in children with moderate to severe TBI. These results can be utilized to enhance the management and care provided to these patients.
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Received: 2023/07/17 | Accepted: 2023/11/22 | Published: 2024/06/30
Received: 2023/07/17 | Accepted: 2023/11/22 | Published: 2024/06/30
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